Introduction
Postoperative complications and prolonged length of stay (LOS) is common following radical cystectomy. Enhanced recovery (ER) is increasingly adopted and improves perioperative outcomes. We investigate the impact of ER and mode of surgery on LOS.
Methods
Between Feb 2009 and Oct 2017, 334 radical cystectomy cases were performed at our institution (98 ORC, 236 RARC). We identified 45 consecutive ORC cases performed without ER before the commencement of the RARC programme (Cohort A), 50 consecutive iRARC cases performed without an ER pathway (Cohort B) and 40 iRARC cases with a well-structured ER pathway (Cohort C). Primary outcome measure was LOS while secondary outcome measures included perioperative 30-day complications and readmission rates. Complications were accessed using the Clavian-Dindo classification.
Results
There were significant differences in median LOS between Cohort A (16 days, IQR: 12.5-20.5), Cohort B (10.0 days, IQR: 7-15.0) and Cohort C (7 days, IQR: 7.0-10.0) (p=0.007). Significantly more cases of continent urinary diversion were performed in Cohort C (35.5%, 11/40) compared to Cohort A (15.6%, 7/45) and Cohort B (20%, 10/50). There was no significant difference in 30-day readmission rates and 30-day mortality although 30-day perioperative complications were significantly lower in Cohort C.
Conclusion
A structured ER programme can significantly reduce LOS in patients undergoing iRARC without increasing 30-day readmission rates. In studies comparing ORC and RARC, the presence or absence of an ER programme will be a confounding factor when interpretating perioperative outcomes following ORC and RARC and only level I evidence can be interpreting reliably.