Rezūm water vapour thermal therapy for benign prostatic hyperplasia: early results from the United Kingdom
BAUS ePoster online library. Johnston M. Jun 27, 2018; 211363; P8-2 Disclosure(s): Educational grant received from Kebomed UK.
Mr. Maximilian Johnston
Mr. Maximilian Johnston
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Abstract
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Introduction: The Rezūm System is a novel minimally invasive thermal therapy for the treatment of symptomatic BPH. We evaluated this new transurethral therapy in patients with moderate to severe symptoms.

Materials & Methods: Ongoing prospective registry evaluation of the first 67 consecutive cases performed in the UK at two centres. All patients had moderate or severe symptoms. Prostate volumes ranged from 22-110mls; patients with an obstructing median lobe and those in retention were included. Pre- and post-procedure assessments included the IPSS questionnaire with quality of life (QOL), urinary flow rate (Qmax), prostate volume and indwelling catheter presence.

Results: 36 of 67 procedures were performed under local anaesthetic with sedation. At 3 months, mean IPSS was significantly improved (-13.1 points)(p<0.001) as was IPSS-QOL (p<0.001). Qmax improved by 6mL/s at 4-6 weeks, 8.4mL/s at 3 months, p<0.001 and 8.8ml/s at 6 months, p=0.002.. Prostate volume was reduced by 36% at 3 months, p=0.002. After first trial without catheter, 56/67 (84%) were successful; at 3 months 65/67 (97%) were catheter free. Using the Clavien-Dindo system there were two grade II complications (UTI requiring antibiotics), three grade 3b (two patients returned to theatre for clot retention 1 month post operatively, and one had transurethral resection of infected prostate tissue at 3 weeks).

Conclusions: Preliminary results of this UK experience with the Rezūm procedure demonstrate significant improvement of LUTS. It can be performed reliably as a day case procedure. Longer term follow-up is required and will include the comparison of outcomes to standard BPH treatments.

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