3 years follow up results of MediTate® temporary implantable nitinol device (TIND) implantation for the BPH related bladder outlet obstruction treatment
BAUS ePoster online library. Amparore D. Jun 27, 2018; 211370
Dr. Daniele Amparore
Dr. Daniele Amparore
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Abstract
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Objectives: To report 3 years outcomes of a prospective study on Temporary Implantable Nitinol Device (TIND - Meditate®) implantation for the treatment of lower urinary tract symptoms (LUTS).

Methods: The TIND, in its expanded configuration, exerts radial force producing incisions of the bladder neck.
Thirty-two patients with LUTS were enrolled. Inclusion criteria: age >50 years, IPSS scores of ≥10, urinary peak flow (Qmax) < 12 ml/sec, prostate volume < 50 cc. TIND was implanted under light sedation using a rigid 22F cystoscope and removed 5 days later in an outpatient setting.
Demographics, perioperative, functional results, complications and quality of life (QoL) were evaluated. For the purpose of this study 12, 24 and 36 months postoperatively results are reported.

Results: Patients' mean age was 69.4 years, mean prostate volume, median IPSS score, median QoL and mean Qmax were 29.5 cc, 19, 3, and 7.6 ml/sec respectively. No complications were recorded during implantations and retrievals. After 12 months, IPSS score, QoL and Qmax were 9, 1 and 12 ml/sec respectively. When comparing pre- and 1 year postoperative results were statistically different for all variables.
After 24 months IPSS score, QoL and Qmax were 10, 2, and 13.7 ml/sec respectively, while after 36 months IPSS score, QoL and Qmax were 12, 2 and 13 ml/sec. After 3 years, mean variation with respect to baseline conditions in term of Qmax was +71%.

Conclusion: TIND implantation seem to be an effective minimally-invasive option for the treatment of LUTS even after 3 years of follow up.
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