IDENTIFY: The Investigation and DEtection of urological Neoplasia in paTIents reFerred with suspected urinarY tract cancer: A multicentre analysis
BAUS ePoster online library. Khadhouri S. Jun 24, 2019; 259504; P2-1
Mr. Sinan Khadhouri
Mr. Sinan Khadhouri
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Abstract
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Aims:

To determine contemporary urinary tract cancer rates and diagnostic test performance in patients referred to secondary care with suspected urothelial cancer.

Materials & Methods

IDENTIFY is the largest ever prospective, international study of patients referred to secondary care with haematuria. Extensive data on patient demographics, presenting features and diagnostic test results were recorded.

RESULTS


11,130 patient records were collected from 111 hospitals in 28 countries (Dec 2017 - Dec 2018). The prevalence of bladder cancer [BC] overall was 14.2%; 18.1% in VH, 3.7% in NVH. Upper tract urothelial cancer [UTUC] prevalence was 1% overall, renal cell carcinoma [RCC] 0.9% and prostate cancer 1.2%.

Variables significantly associated with BC included type of haematuria, age, smoking history, anticoagulation, storage urinary tract symptoms and having had >1 episode of VH (25.5%) vs. only 1 (17.9%). UTUC was significantly associated with type of haematuria, age, smoking and anticoagulation. The rate of BC found in those with culture proven urinary tract infection [UTIs] was 7.0%, which was significantly lower than in those without UTI (19.7%). The diagnostic performance of ultrasound [US] and Computed Tomography [CT] is given in Table 1.

Conclusions

IDENTIFY provides contemporary cancer detection rates in a global population alongside extensive predictive data and diagnostic test performance for each cancer type. The detailed data will allow complex interactions between predictive variables to be appreciated and develop a personalised approach to haematuria investigations. This should improve shared decision-making and optimise cancer detection whilst minimising investigative burden.
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