Penile Transplantation: The Long And Short Of It
BAUS ePoster online library. Reis I. Jun 25, 2019; 259559; P6-5
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Ines Reis
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Traumatic or iatrogenic penile loss has serious physical and emotional consequences for patients and is typically managed with free flap phalloplasty. However, advances in composite tissue allotransplantation have lead to the development of penile transplantation as an alternative approach.

Material and Methods

A comprehensive literature search relating to the history of penile transplantation was undertaken.


Penile transplantation was first attempted in China in 2006 in a 44-year old man with traumatic penile amputation. Although technically successful, the patient underwent removal of the graft 2 weeks later due to psychological distress. Andre van der Merwe at Stellenbosch University in South Africa is credited with performing the world's first successful penile transplant in 2014. The patient, who had suffered partial loss of his penis from complications of a circumcision, was able to impregnate his partner within a year post-transplantation. In 2017, the unit performed a second transplant, making it the first centre to successfully perform this procedure twice. In the same year, surgeons at Massachusetts General Hospital in Boston transplanted a 64-year old man who had undergone a penectomy for penile cancer. A year later, the first total penile and scrotum transplant was performed at Johns Hopkins on a combat victim with severe genitourinary trauma from a blast injury.


Although penile transplantation is still in its infancy, encouraging short-term outcomes have been reported in recipients. Nevertheless, long-term results are awaited and consensus is needed regarding ethical issues surrounding this novel procedure.
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